Higher education within the United States is in the midst of an evolutionary change. But colleges and universities were having their moment of reckoning long before COVID-19 disrupted life and accelerated change. In the fall of 2020, SCUP’s Pacific Region held five sessions over eight weeks to explore the core topics shaping higher education as colleges and universities adapted in response to the pandemic. This publication offers key insights, findings, and questions from this Virtual Pacific Region Fall Series.